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Raymond F Schinazi Selected Research

Nucleosides

1/2022Baricitinib attenuates the proinflammatory phase of COVID-19 driven by lung-infiltrating monocytes.
4/2021Baicalein and Baicalin Inhibit SARS-CoV-2 RNA-Dependent-RNA Polymerase.
1/2021Moving Fast Toward Hepatitis B Virus Elimination.
1/2021Comparison of anti-SARS-CoV-2 activity and intracellular metabolism of remdesivir and its parent nucleoside.
3/2020Synthesis of 4'-Substituted-2'-Deoxy-2'-α-Fluoro Nucleoside Analogs as Potential Antiviral Agents.
1/20207-Deaza-7-fluoro-2'-C-methyladenosine inhibits Zika virus infection and viral-induced neuroinflammation.
1/2020Potent in vitro activity of β-D-4'-chloromethyl-2'-deoxy-2'-fluorocytidine against Nipah virus.
1/2019Nucleoside Analogs with Selective Antiviral Activity against Dengue Fever and Japanese Encephalitis Viruses.
10/2017Metabolism of Nucleosides and Nucleotides Prodrugs.
12/2016Metabolism, Biochemical Actions, and Chemical Synthesis of Anticancer Nucleosides, Nucleotides, and Base Analogs.
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Raymond F Schinazi Research Topics

Disease

35Infections
01/2022 - 05/2002
16Neoplasms (Cancer)
10/2021 - 01/2004
14COVID-19
12/2022 - 05/2020
14Acquired Immunodeficiency Syndrome (AIDS)
01/2022 - 04/2002
12HIV Infections (HIV Infection)
10/2022 - 01/2003
9Inflammation (Inflammations)
01/2022 - 05/2015
6Body Weight (Weight, Body)
12/2021 - 01/2005
5Virus Diseases (Viral Diseases)
11/2021 - 07/2014
5Hepatocellular Carcinoma (Hepatoma)
06/2021 - 07/2005
5Chronic Hepatitis C
06/2021 - 12/2013
5Chronic Hepatitis B
01/2021 - 05/2002
4Hepatitis C
02/2014 - 01/2006
3Viremia
01/2014 - 09/2007
3Parasitic Diseases (Parasitic Disease)
12/2006 - 06/2003
2Fibrosis (Cirrhosis)
01/2021 - 10/2016
2Neuroinflammatory Diseases
01/2020 - 09/2019
2Zika Virus Infection
01/2020 - 01/2017
2Encephalitis (Encephalitis, Rasmussen)
01/2020 - 01/2016
2Gliosis
09/2019 - 01/2016
2Rheumatoid Arthritis
09/2019 - 01/2014
2Dengue (Dengue Fever)
01/2019 - 01/2006
2Drug-Related Side Effects and Adverse Reactions
01/2019 - 12/2012
2Ovarian Neoplasms (Ovarian Cancer)
01/2018 - 11/2017
2Primary Myelofibrosis (Myelosclerosis)
01/2016 - 01/2014
2Liver Diseases (Liver Disease)
07/2014 - 11/2013
2Communicable Diseases (Infectious Diseases)
07/2014 - 12/2006
2Opportunistic Infections (Opportunistic Infection)
05/2010 - 08/2004
2Prostatic Neoplasms (Prostate Cancer)
04/2010 - 01/2004
2T-Cell Lymphoma (Lymphoma, T Cell)
06/2007 - 07/2005
2Diarrhea
01/2003 - 12/2002
1Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
01/2022
1Disease Progression
01/2022
1Gastroenteritis
12/2020
1Hepatitis B
03/2020
1Cardiotoxicity
01/2020

Drug/Important Bio-Agent (IBA)

27NucleosidesIBA
01/2022 - 01/2003
25Antiviral Agents (Antivirals)IBA
12/2022 - 01/2003
16Pharmaceutical PreparationsIBA
12/2022 - 05/2002
8baricitinibIBA
01/2022 - 09/2019
8RNA (Ribonucleic Acid)IBA
10/2021 - 01/2003
7ruxolitinibIBA
01/2022 - 01/2014
7CytokinesIBA
12/2021 - 09/2019
6InterferonsIBA
01/2022 - 07/2014
5DNA (Deoxyribonucleic Acid)IBA
12/2020 - 09/2007
5NucleotidesIBA
01/2020 - 05/2010
5Lamivudine (Epivir)FDA Link
01/2007 - 05/2002
4remdesivirIBA
01/2022 - 10/2020
4Janus Kinase InhibitorsIBA
01/2022 - 01/2016
4Proteins (Proteins, Gene)FDA Link
11/2021 - 05/2020
4RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
11/2015 - 06/2005
3RacivirIBA
01/2022 - 05/2002
3EnzymesIBA
10/2021 - 01/2015
3Ribavirin (Virazole)FDA LinkGeneric
06/2021 - 04/2004
3VaccinesIBA
01/2021 - 01/2017
3RNA-Dependent RNA Polymerase (RNA Dependent RNA Polymerase)IBA
01/2021 - 02/2014
3SofosbuvirIBA
01/2020 - 07/2014
3Reverse Transcriptase InhibitorsIBA
11/2015 - 07/2012
2Emtricitabine (Emtriva)FDA Link
01/2022 - 12/2012
2SAM Domain and HD Domain-Containing Protein 1IBA
01/2022 - 10/2021
2Biomarkers (Surrogate Marker)IBA
01/2022 - 10/2021
2Aspartic Acid (Aspartate)FDA Link
10/2021 - 12/2020
2Histidine (L-Histidine)FDA Link
10/2021 - 12/2020
2ChemokinesIBA
01/2021 - 09/2020
2Interferon-alpha (Interferon Alfa)IBA
01/2021 - 04/2004
2ProdrugsIBA
01/2021 - 01/2008
2AntigensIBA
01/2021 - 11/2013
2Peptide Hydrolases (Proteases)FDA Link
01/2019 - 01/2018
2Viral RNAIBA
01/2018 - 07/2010
2Paclitaxel (Taxol)FDA LinkGeneric
01/2018 - 11/2017
2Protease Inhibitors (Protease Inhibitor)IBA
10/2016 - 12/2013
2SimeprevirIBA
10/2016 - 07/2014
2ThymidineIBA
07/2012 - 05/2010
2Stavudine (Zerit)FDA LinkGeneric
11/2011 - 03/2009
2phytobacteriomycin (PBM)IBA
06/2007 - 07/2005
2triphosphoric acid (triphosphate)IBA
06/2007 - 05/2002
2Biological ProductsIBA
12/2006 - 08/2004
2UridineIBA
11/2006 - 06/2005
2Fluorouracil (Carac)FDA LinkGeneric
11/2006 - 06/2005
2AlkaloidsIBA
08/2004 - 06/2003
1Chloroquine (Aralen)FDA LinkGeneric
12/2022
1Viral ProteinsIBA
01/2022
1Lipopolysaccharide ReceptorsIBA
01/2022
1Messenger RNA (mRNA)IBA
01/2022
1Cytochrome P-450 CYP3AIBA
12/2021
1Janus Kinase 1IBA
12/2021
1efavirenz (Sustiva)FDA Link
12/2021
1LigandsIBA
11/2021
1baicalinIBA
04/2021
1baicaleinIBA
04/2021
1GS-441524IBA
01/2021
1Hydroxychloroquine (Plaquenil)FDA LinkGeneric
01/2021
1Dexamethasone (Maxidex)FDA LinkGeneric
01/2021
1Immunoglobulin M (IgM)IBA
05/2020
1Immunoglobulin G (IgG)IBA
05/2020

Therapy/Procedure

24Therapeutics
01/2022 - 05/2002
9Highly Active Antiretroviral Therapy (HAART)
10/2022 - 05/2002
3Art Therapy
01/2018 - 01/2015
2Drug Therapy (Chemotherapy)
01/2019 - 11/2017
2Oral Administration
09/2007 - 07/2007
2Boron Neutron Capture Therapy
09/2005 - 01/2004